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KMID : 1103720130680050397
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Journal of the Korean Society of Radiology
2013 Volume.68 No. 5 p.397 ~ p.405
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Relationship between Conventional Cardiovascular Disease Risk Assessment and Coronary Artery Calcification in Group Exposed to Inorganic Dusts
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Lee Won-Jeong
Park So-Young
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Abstract
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Purpose: The purpose of this study is to determine the relationship between the coronary artery calcification (CAC) and the conventional cardiovascular disease risk assessment (CCDRA).
Materials and Methods: This study included 101 subjects who were exposed to inorganic dusts and underwent CAC scoring by multidetector CT (MDCT), laboratory tests, and a standardized questionnaire for CCDRA, after being approved from the Institutional Review Board and providing informed consent. All subjects were divided as either non-calcified group (< 1, 55.4%) or calcified group (≥ 1, 44.6%) from total CAC, and evaluated by CCDRA, such as Framingham risk score (FRS) and National Cholesterol Education Program (NCEP). Receiver operating characteristic (ROC) area of FRS was generated for predicting CAC risk using SPSS program (ver. 19.0, Chicago, IL, USA).
Results: Total CAC was significantly correlated with FRS (r = 0.283, p = 0.004). Crude odds ratio for CAC risk was 3.64 [95% confidence interval (CI) 1.39-9.52] in FRS ≥ 20%, and 2.87 (95% CI 1.24-6.65) in the high risk group of NCEP. Subjects with pneumoconiosis showed higher values of CAC (p = 0.541) and FRS (p = 0.035) scores compared with subjects without pneumoconiosis. ROC area of FRS was 0.69 (95% CI 0.59-0.79) with a cutoff point of 13.5%.
Conclusion: CAC measured MDCT is significantly correlated with FRS than other CCDRA
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KEYWORD
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Cardiovascular Disease Risk Assessment, Coronary Artery, Computed Tomography, Pneumoconiosis, Vascular Calcification
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